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Gene Symbol e.g. SHC1
Protein Name e.g. EGF receptor
Accession Number e.g. NP_002077
Pathway Name
 Curated Pathways  36
 Molecules Involved  1053
 Physical Interactions  2448
 Genes Transcriptionally Regulated  7401
 Transport  284
 Enzyme Catalysis  1597
 PubMed Citations  2228

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'NetPath' is a manually curated resource of signal transduction pathways in humans. It is a collaborative effort between the PandeyLab at Johns Hopkins University and the Institute of Bioinformatics. The initial set of 10 cancer signaling pathways were developed in collaboration with the Computational Biology Center at Memorial Sloan-Kettering Cancer Center and with Gary Bader's lab at the University of Toronto for the 'Cancer Cell Map'.
All pathways in NetPath are freely available for download in BioPAX level 3.0, PSI-MI version 2.5 and SBML version 2.1 formats at this website. The slim pathway models representing only core reactions in each pathway are available at NetSlim. All the NetPath pathway models are also submitted to WikiPathways. The pathway data are freely available under an adaptive Creative Commons License which stipulates that the pathways may be used if adequate credit is given to the authors.
Please cite the following reference for this database:
Kandasamy, K. and Mohan, SS. et al. (2010) NetPath: A public resource of curated signal transduction pathways. Genome Biology. 11:R3.[PubMed]
Please cite the reference for the specific pathways in NetPath (Publications)
Feedback on the NetPath website and its contents can be sent to info at netpath dot org.
This is a joint project between: